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Oestrogel is a hormone replacement therapy that is used to treat the symptoms of menopause. The gel contains the hormone estriol, which is absorbed through the skin and enters the bloodstream. Estriol works by replacing the natural hormone estrogen that is no longer being produced by the body during menopause, and this can help to relieve symptoms associated with menopause. Estriol helps to restore the balance of hormones in the body, which can relieve the symptoms of menopause. It can also help to protect against osteoporosis and heart disease.